microRNA在昆虫翅发育及生殖中的研究进展
Progress in research on the role of microRNA in insect wing development and reproduction
葛爽爽1, 2 ** 董瑞文3 赵 洁2 刘 梅2 吴宜丹1, 2 刘 梦4 贠 静4 林克剑2*** 高书晶2***
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DOI：10.7679/j.issn.2095-1353.2025.136
作者单位：1. 青岛农业大学，青岛 266109；2. 中国农业科学院草原研究所，农业农村部人工草地生物灾害监测与绿色防控重点实验室， 呼和浩特 010010；3. 乌兰察布盟四子王旗草原站，乌兰察布 011800；4. 新疆畜牧科学院草业研究所，乌鲁木齐 830000
中文关键词：microRNA；转录后调节；翅发育；生殖；昆虫
英文关键词： microRNA; post-transcriptional regulation; wing development; reproduction; insect
中文摘要：
microRNA（miRNA）是内源性、约22个核苷酸长、单链非编码RNA，主要通过与信使RNA 3'非翻译区（Untranslated region，UTR）中互补的种子序列（miRNA 5'端的第2到第8个核苷酸）进行碱基配对，在转录后调控基因表达。在昆虫中，miRNA已被证明在昆虫发育过程中调节包括变态、卵子发生、行为和宿主-病原体相互作用等多种生理过程。近年来，重要农业昆虫中miRNA功能的研究引起了人们的广泛关注，本文在简要介绍miRNA生物合成与作用方式的基础上，重点介绍了近年来有关miRNA在昆虫翅发育和生殖中的研究进展，以期为更全面地了解昆虫miRNA，促进其在害虫防治中的应用提供参考。
英文摘要：
microRNAs
(miRNAs) are endogenous, single-stranded non-coding RNAs of about 22
nucleotides in length. They regulate gene expression post-transcriptionally by
base pairing with complementary seed sequences (2nd to 8th nucleotides at the
5' end of miRNAs) in the 3' untranslated region (UTR) of mRNA. In insects,
miRNAs have been shown to regulate a variety of physiological processes
including metamorphosis, oogenesis, behavior, and host-pathogen interactions
during development. In recent years, research on the function of miRNAs in
important agricultural insects has attracted widespread attention. Based on a
brief introduction of miRNA biosynthesis and their mechanism of action, this
paper focuses on recent progress in research on the role of miRNAs in insect
reproduction and wing development with the aim of improving the understanding
of insect miRNAs and promoting their application in pest control.